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  • 徐邹峰

    研究助理教授

    • 邮箱：xuzf3@sustech.edu.cn

    办公室：南方科技大学创园五栋

    个人主页：

    http://faculty.sustech.edu.cn/xuzf3/


    • 基本介绍
    • 研究方向
    • 学术成果
    • 其它信息
    教育背景：
    2014.09—2019.12        香港城市大学 化学博士
    2011.09—2014.07        中科院成都有机化学研究所 有机化学硕士
    2007.09—2011.07        吉林大学 化学学士

    工作经历：
    2024.08  至今               南方科技大学 研究助理教授
    2021.09—2024.07        深圳湾实验室 助理研究员
    2020.01—2021.07        亚利桑那大学 博士后

    有机化学，配位化学，药物化学
    1. Xu, Zoufeng†; Sung, Y.†; Tomat, E., Design of tetrazolium cations for the release of antiproliferative formazan chelators in mammalian cells. Journal of the American Chemical Society, 2023, 145, 15197-15206. https://doi.org/10.1021/jacs.3c02033
    2. Xu, Zoufeng†; Lin L.†; Fu B.; Huang F.; Zhou Q.; Zhu G.; Wang, Z., Ligand substitution reactions afford oxaliplatin-based platinum(IV) complexes bearing axial alkoxido ligands. Inorganic Chemistry Frontiers, 2023. 10, 6058-6066. https://doi.org/10.1039/D3QI01562A
    3. Xu, Zoufeng; Wang, Z.; Deng, Z.; Zhu, G., Recent advances in the synthesis, stability, and activation of platinum(IV) anticancer prodrugs. Coordination Chemistry Reviews, 2021, 442, 213991. https://doi.org/10.1016/j.ccr.2021.213991
    4. Xu, Zoufeng; Tang, W. K.; Zhou, Q.; Chen, S.; Siu, C.-K.; Zhu, G., On the hydrolytic stability of unsymmetric platinum(IV) anticancer prodrugs containing axial halogens. Inorganic Chemistry Frontiers, 2021, 8, 3794-3802. https://doi.org/10.1039/D1QI00208B
    5. Xu, Zoufeng†; Li, C.†; Zhou, Q.; Deng, Z.; Tong, Z.; Tse, M.-K.; Zhu, G., Synthesis, cytotoxicity, and mechanistic investigation of platinum(IV) anticancer complexes conjugated with poly(ADP-ribose) polymerase inhibitors. Inorganic Chemistry, 2019, 58, 16279-16291. https://doi.org/10.1021/acs.inorgchem.9b02839
    6. Xu, Zoufeng; Chan, H. M.; Li, C.; Wang, Z.; Tse, M.-K.; Tong, Z.; Zhu, G., Synthesis, structure, and cytotoxicity of oxaliplatin-based platinum(IV) anticancer prodrugs bearing one axial fluoride. Inorganic Chemistry, 2018, 57, 8227-8235. https://doi.org/10.1021/acs.inorgchem.8b00706
    7. Xu, Zoufeng; Li, C.; Tong, Z.; Ma, L.; Tse, M.-K.; Zhu, G., Halogenated PtIV complexes from N-halosuccinimide oxidation of PtII antitumor drugs: synthesis, mechanistic investigation, and cytotoxicity. European Journal of Inorganic Chemistry, 2017, 2017, 1706-1712. https://doi.org/10.1002/ejic.201601130
    8. Xu, Zoufeng; Wang, Z.; Yiu, S.-M.; Zhu, G., Mono- and di-bromo platinum(iv) prodrugs via oxidative bromination: synthesis, characterization, and cytotoxicity. Dalton Transactions, 2015, 44, 19918-19926. https://doi.org/10.1039/C5DT03101J
    Patent：
    1. Tomat E., Xu Zoufeng, and Sung Y.-S., (2024) Tetrazolium and formazan compounds and methods of making and using the same. Patent No.: WO2024035831A1
    2. Zhu G., Xu Zoufeng, and Zhou Q., (2024) Platinum complex, its preparation and therapeutic use. Patent No.: US20210371441A1
    3.Zhu G., Wang Z., and Xu Zoufeng, (2021) Platinum complex, its preparation and therapeutic use. Patent No.: US10899781B2
    4. Xun X., Ge G., Xu Zoufeng (2015) A synthetic method for cis-2-fluorocyclopropylamine. CN Patent, CN 
    106146319 A

徐邹峰研究助理教授

邮箱：xuzf3@sustech.edu.cn

办公室：南方科技大学创园五栋

个人主页：

http://faculty.sustech.edu.cn/xuzf3/


  • 基本介绍
  • 研究方向
  • 代表性论文
  • 其它信息
教育背景：
2014.09—2019.12        香港城市大学 化学博士
2011.09—2014.07        中科院成都有机化学研究所 有机化学硕士
2007.09—2011.07        吉林大学 化学学士

工作经历：
2024.08  至今               南方科技大学 研究助理教授
2021.09—2024.07        深圳湾实验室 助理研究员
2020.01—2021.07        亚利桑那大学 博士后

有机化学，配位化学，药物化学
1. Xu, Zoufeng†; Sung, Y.†; Tomat, E., Design of tetrazolium cations for the release of antiproliferative formazan chelators in mammalian cells. Journal of the American Chemical Society, 2023, 145, 15197-15206. https://doi.org/10.1021/jacs.3c02033
2. Xu, Zoufeng†; Lin L.†; Fu B.; Huang F.; Zhou Q.; Zhu G.; Wang, Z., Ligand substitution reactions afford oxaliplatin-based platinum(IV) complexes bearing axial alkoxido ligands. Inorganic Chemistry Frontiers, 2023. 10, 6058-6066. https://doi.org/10.1039/D3QI01562A
3. Xu, Zoufeng; Wang, Z.; Deng, Z.; Zhu, G., Recent advances in the synthesis, stability, and activation of platinum(IV) anticancer prodrugs. Coordination Chemistry Reviews, 2021, 442, 213991. https://doi.org/10.1016/j.ccr.2021.213991
4. Xu, Zoufeng; Tang, W. K.; Zhou, Q.; Chen, S.; Siu, C.-K.; Zhu, G., On the hydrolytic stability of unsymmetric platinum(IV) anticancer prodrugs containing axial halogens. Inorganic Chemistry Frontiers, 2021, 8, 3794-3802. https://doi.org/10.1039/D1QI00208B
5. Xu, Zoufeng†; Li, C.†; Zhou, Q.; Deng, Z.; Tong, Z.; Tse, M.-K.; Zhu, G., Synthesis, cytotoxicity, and mechanistic investigation of platinum(IV) anticancer complexes conjugated with poly(ADP-ribose) polymerase inhibitors. Inorganic Chemistry, 2019, 58, 16279-16291. https://doi.org/10.1021/acs.inorgchem.9b02839
6. Xu, Zoufeng; Chan, H. M.; Li, C.; Wang, Z.; Tse, M.-K.; Tong, Z.; Zhu, G., Synthesis, structure, and cytotoxicity of oxaliplatin-based platinum(IV) anticancer prodrugs bearing one axial fluoride. Inorganic Chemistry, 2018, 57, 8227-8235. https://doi.org/10.1021/acs.inorgchem.8b00706
7. Xu, Zoufeng; Li, C.; Tong, Z.; Ma, L.; Tse, M.-K.; Zhu, G., Halogenated PtIV complexes from N-halosuccinimide oxidation of PtII antitumor drugs: synthesis, mechanistic investigation, and cytotoxicity. European Journal of Inorganic Chemistry, 2017, 2017, 1706-1712. https://doi.org/10.1002/ejic.201601130
8. Xu, Zoufeng; Wang, Z.; Yiu, S.-M.; Zhu, G., Mono- and di-bromo platinum(iv) prodrugs via oxidative bromination: synthesis, characterization, and cytotoxicity. Dalton Transactions, 2015, 44, 19918-19926. https://doi.org/10.1039/C5DT03101J
Patent：
1. Tomat E., Xu Zoufeng, and Sung Y.-S., (2024) Tetrazolium and formazan compounds and methods of making and using the same. Patent No.: WO2024035831A1
2. Zhu G., Xu Zoufeng, and Zhou Q., (2024) Platinum complex, its preparation and therapeutic use. Patent No.: US20210371441A1
3.Zhu G., Wang Z., and Xu Zoufeng, (2021) Platinum complex, its preparation and therapeutic use. Patent No.: US10899781B2
4. Xun X., Ge G., Xu Zoufeng (2015) A synthetic method for cis-2-fluorocyclopropylamine. CN Patent, CN 
106146319 A