何振宇，南方科技大学化学系教授、研究员；Grubbs 研究院双聘教授；何振宇博士于2000年-2005年在香港大学（the university of hong kong）化学系杨丹教授指导下从事有机不对称催化并获得博士学位，随后在麻省理工学院（M.I.T.） prof. timothy f. jamison研究组作为博士后从事过渡金属催化。从2007年底开始，在香港中文大学（the chinese university of hongkong）作为研究助理教授开始了独立的研究，从2013年起，加盟深圳南方科技大学(SUSTech)，入选深圳市孔雀计划b类人员，主要从事金属有机化学n-杂环卡宾及其在有机金属催化中的应用研究，在国内外学术刊物（angew. chem. int. ed, j. am.chem. soc，chem. commun., acs catal.等）发表论文多篇，并获the asian core program lectureship award (from japan)，the asian core program lectureship award (from singapore)等多项奖项。

新材料产业—先进石化工新材料—专用化学品及材料制造—专用化学品及材料制造

Publications：

(35). (NHC)Ni(II) directed insertions and higher olefin synthesis from olefins. Zhang, Z. F; Chen. Y; Gu, X;Ho, C.-Y.* Acc. Chem. Res. 2023, 56, 1087.

(34). Our Voyage from Catalytic Cross-Hydroalkenylation to Transfer-Dehydroaromatization of Cyclic pi-Systems: Reactivity and Selectivity Changes Enabled by NHC-Ni and NHC-Pd Hydride Equivalents. Chen, Y.;Chen. W.;Gu, X.;Ho, C.-Y.* Synlett. 2023, 34, 1639.

(33). Unsymmetric N-Aryl Substituent Effects on Chiral NHC-Cu: Enantioselectivity and Reactivity Enhancement by Ortho-H and Syn-Configuration. Xi, J.; Ng, E. W. H.; Ho, C.-Y.* ACS Catal. 2023, 13, 407.

Highlighted in X-mol. 

(32). (NHC)Pd(II) hydride-catalyzed dehydroaromatization by Olefin Chain-Walking Isomerization and Transfer-Dehydrogenation. Chen. W.; Chen, Y.; Gu, X.; Chen, Z.; Ho, C.-Y.* Nat. Commun. 2022, 13, 5507.

Highlighted in X-mol & Chemstation.

(31). NHC-Ni(II)-Catalyzed Cyclopropene-Isocyanide [5+1] Benzannulation. Huang, J.-Q.; Yu, M.; Yong, X.; Ho, C.-Y.* Nat. Commun. 2022, 13, 4145.

Highlighted in X-mol.

(30). Diastereodivergent Hydrosilylative Enyne Cyclization Catalyzed by N-Heterocyclic Carbene-Ni(0). Yu, M.; Yong, X.; Gao, W.; Ho, C.-Y.* Chin. J. Chem. 2021, 39, 1587.

(Special Issue: SUSTech 10th Anniversary/南科大化学系十周年纪念专辑)

(29). NHC/Nickel(II)-Catalyzed [3+2] Cross-Dimerization of Unactivated Olefins and Methylenecyclopropanes. Huang, J.-Q.; Ho, C.- Y.* Angew. Chem. Int. Ed. 2020, 59, 5288.

Highlighted in X-mol.

(28). NHC-Ni catalyzed enantioselective synthesis of 1,4-dienes by cross-hydroalkenylation of cyclic 1,3-dienes and heterosubstituted terminal olefins. Chen, Y.; Dang, L.; Ho, C.- Y.* Nat. Commun. 2020, 11 , 2269.

(27). NHC-Ni catalyzed 1,3- and 1,4-diastereodivergent heterocycle synthesis from hetero-substituted enyne. Yong, X.; Gao, W.; Lin, X.; Ho, C.- Y.* Comm. Chem. 2020, 3 , 50.

(26). NHC-Ni(0) Catalyzed Diastereodivergent Hydroacylative Enyne Cyclization: Synthesis of Heterocycles bearing gamma-Enone. Yong, X.; Ng, E.; Zhen, Z.; Lin, X.; Gao, W.; Ho, C.-Y.* Adv. Synth. Cat. 2020, 362 , 4164.

(25). Applications of (NHC)Ni(II) Catalyzed [3+2] Hydroalkenylation-Rearrangement Cascades. Yong, X.; Huang, J.-Q., Ho, C.- Y.* Chin. J. Org. Chem. 2020, 40, 3327.

(Special Issue: Professor Henry N. C. Wong on the occasion of his 70th birthday)

(24). [(NHC)Ni(II)H]-Catalyzed Cross-Hydroalkenylation of Cyclopropenes with Alkynes: Cyclopentadiene Synthesis by [(NHC)Ni(II)]-Assisted C-C Rearrangement. Huang, J.-Q.; Ho, C.-Y.* Angew. Chem. Int. Ed. 2019, 58, 5702.

Featured as Inside Cover in Angew. Chem. Int. Ed. 2019, 58, 5466.

(23). Electronic Effects on Chiral NHC–Transition-Metal. Yong, X., Thurston, R. & Ho, C.-Y.* Synthesis. 2019, 51, 2058.

(22). Synthesis and Study of Au(III)-Indolizine Derivatives: Turn-on Luminescence by Photo-induced Control Release. Yang, J.; Zhu, Y.; Tse, A. K.-W.; Zhou, X.; Chen, Y.; Tse, Y. C.;* Wong, K. M.-C.;* Ho, C.-Y.* Chem. Commun. 2019, 55, 4471.

(21). Intranasal delivery of a novel acetylcholinesterase inhibitor HLS-3 for treatment of Alzheimer’s disease. Qian, S.; He, .; Wang, Q.; Wong, Y. C.; Mak, M.; Ho, C.-Y.*; Han, Y.*; Zuo, Z*. Life Sciences 2018, 207, 428.

(20). (NHC)NiH-Catalyzed Regiodivergent Cross-Hydroalkenylation of Vinyl Ether with α-Olefin: 1,2- and 1,3-Disubstituted Allyl Ether Syntheses. Chen, W.; Li, Y.; Chen, Y.; Ho, C.-Y.* Angew. Chem. Int. Ed. 2018, 57, 2677.

Highlighted in X-mol & Chin. J. Org.Chem.

(19). (NHC)NiH-Catalyzed Intermolecular Regio- and Diastereoselective Cross-Hydroalkenylation of Endocyclic Dienes with α-Olefins. Lian, X.; Chen, W.; Dang, L.; Li, Y.; Ho, C.-Y.* Angew. Chem. Int. Ed. 2017, 56, 9048.

Highlighted in X-mol.

(18). Mechanism and Regioselectivities of (NHC)Nickel(II)hydride-Catalyzed Cycloisomerization of Dienes: A Computational Study. Gao, Y.; Houk, K. N.; Ho, C.-Y.*; Hong, X.* Org. Biomol. Chem. 2017, 15, 7131.

Themed Collections: Mechanistic Aspects of Organic Synthesis

(17). Catalytic Asymmetric Hydroalkenylation of Vinylarenes: Electronic Effects of Substrates and Chiral N-Heterocyclic Carbene Ligands Ho, C.-Y.*; Chan, C.-W.; He, L. Angew. Chem. Int. Ed. 2015, 54, 4512.

Featured as Front Cover & VIP (Very Important Paper),

in Angew. Chem. Int. Ed. 2015, 54 (15), 4403.

in ChemCatChem 2015, 7, 1639 by Prof. Gerhard Hilt &

in ChemInform (preparative org. chem.) & in X-Mol.

(16). Substituted 1,3-cyclohexadiene synthesis by NHC-Nickel(0) catalyzed [2+2+2] cycloaddition of 1,n-Enyne”. Zhao, J.-P.; Chan, S.-C.; Ho, C.-Y.* Tetrahedron 2015, 71, 4426. Invited Special Symposium-in-Print: Progress in organic synthesis: New reactions, strategies and targets.

(15). Computational Exploration of Mechanism and Selectivities of NHC-Ni(II)hydride Catalyzed Hydroalkenylations of Styrene with a-Olefins. Hong, X.; Wang, J.; Yang, Y.-F.; He, L.; Ho, C.-Y.*; Houk, K. N.* ACS Catal. 2015, 5, 5545.

(14). Nitrate-Enhanced NHC-NiH Catalyzed Tail-to-Tail Vinyl Ether Dimerization. He, L.; Ho, C.-Y.* Synlett 2014, 25, 2738.

Invited Special Issue: Catalysis with Sustainable Metals.

(13). Medium-Sized Heterocycle Synthesis by the Use of Synergistic Effects of Ni-NHC and γ Coordination in Cycloisomerization. Ho, C.-Y.*; He, L. J. Org. Chem. 2014, 79, 11873.

Highlighted thrice:

in SynFacts 2014, 10, 913 (by Prof. V. Snieckus)

in ChemInform (preparative org. chem.)

in Organic Chemistry Highlights, 2015(by Prof. D. F. Taber)“C-O Ring Construction”

(12). Synthesis, biological activity, and biopharmaceutical characterization of tacrine dimers as acetylcholinesterase inhibitors. Qian, S.; He, L.; Mak, M.; Han, Y.*; Ho, C.-Y.*; Zuo, Z.* Int. J. Pharmaceutics, 2014, 477, 442.

(11). Shuffle off the Classic b-Si Elimination by Ni-NHC Cooperation: Implication for C-C Forming Reactions Involving Ni-Alkyl-β-Silanes. Ho, C.-Y.*; He, L. Chem. Commun. 2012, 48, 1481.

Highlighted twice:

in Novo Nordisk & in ChemInform (Organoelement compounds)

(10). Catalytic Intermolecular Tail-to-Tail Hydroalkenylation of Styrenes with alpha Olefins: Regioselective Migratory Insertion Controlled by a Nickel/N-Heterocyclic Carbene. Ho, C.-Y.*; He, L. Angew. Chem. Int. Ed. 2010, 49, 9182.

Highlighted thrice:

in SynForm 2011, issue 2, A15-16 & as Cover (by Prof. M. Zanda);

in SynFacts 2011, issue 3, 310 (by Prof. P. Knochel);

in Organic Chemistry Highlights, 2011 Functionalization & Homologation of Alkenes (by Prof. D. F. Taber)

(9). Cyanative Alkene-Aldehyde Coupling: Ni(0)-NHC-Et2AlCN Mediated Chromanols Synthesis with High cis-Selectivity at room temperature. Ho, C.-Y.* Chem. Commun. 2010, 46, 466.

(8). Nitrile assisted, Bronsted acid catalyzed regio and stereoselective diarylphosphonylation of allyl silyl ethers. Ho, C.-Y.*; Chan, C.-W.; Wo, S.-K.; Zuo, Z.; Chan, L.-Y. Biomol. Chem. 2010, 8, 3480.

Highlighted in ChemInform (organoelement compounds)

(7). Alpha Olefins as Alkenylmetal Equivalents in Catalytic Conjugate Addition Reactions. Ho, C.-Y.; Ohmiya, H.; Jamison, T. F.* Angew. Chem. Int. Ed. 2008, 47, 1893.

(6). Highly Chemoselective Reductive Amination of Carbonyl Compounds Promoted by InCl3/Et3SiH/MeOH System. Lee, O.-Y.; Law, K.-L.; Ho, C.-Y.; Yang, D.* J. Org. Chem. 2008, 73, 8829.

(5). Highly Selective Coupling of Alkenes and Aldehydes Catalyzed by NHC–Ni–P(OPh)3: Synergy Between a Strong σ-Donor and a Strong π-Acceptor. Ho, C.-Y.; Jamison, T. F.* Angew. Chem. Int. Ed. 2007, 46, 782.

Highlighted twice:

in Angew. Chem. Int. Ed. as Hot Paper

in ChemInform (isocyclic compounds)

(4). Nickel-Catalyzed Coupling of Alkenes, Aldehydes, and Silyl Triflates. Ng, S.-S.; Ho, C.-Y.; Jamison, T. F.* J. Am. Chem. Soc. 2006, 128, 11513.

(3). Nickel-Catalyzed, Carbonyl-Ene-Type Reactions: Selective for Alpha Olefins and More Efficient with Electron-Rich Aldehydes. Ho, C.-Y.; Ng, S.-S.; Jamison, T. F.* J. Am. Chem. Soc. 2006, 128, 5326.

Highlighted in ChemInform (isocyclic compounds)

(2). Fluorinated Chiral Secondary Amines as Catalysts for Epoxidation of Olefins with Oxone. Ho, C.-Y.; Chen, Y.-C.; Wong, M.-K.; Yang, D.* J. Org. Chem. 2005, 70, 898.

(1). Asymmetric epoxidation of olefins catalyzed by chiral iminium salts generated in-situ from chiral amines and aldehydes. Wong, M.-K.; Ho, L.-M.; Zheng, Y.-S.; Ho, C.-Y.; Yang, D.* Org. Lett. 2001, 3, 2587.