何振宇博士于2000年-2005年在香港大学(the university of hong kong)化学系杨丹教授指导下从事有机不对称催化并获得博士学位,随后在麻省理工学院(M.I.T.) prof. timothy f. jamison研究组作为博士后从事过渡金属催化。从2007年底开始,在香港中文大学(the chinese university of hongkong)作为研究助理教授开始了独立的研究,从2013年起,加盟深圳南方科技大学(SUSTech),入选深圳市孔雀计划b类人员,主要从事金属有机化学n-杂环卡宾及其在有机金属催化中的应用研究,在国内外学术刊物(angew. chem. int. ed, j. am.chem. soc,chem. commun., acs catal.等)发表论文多篇,并获the asian core program lectureship award (from japan),the asian core program lectureship award (from singapore)等多项奖项。
教育背景:
2000.09-2005.07 —— 博士,香港大学,化学专业 (with Prof. D. Yang)
1997.09-2000.07 —— 学士,香港大学,化学专业
工作经历:
2013.01-至今 —— 副教授,南方科技大学,化学系
2007.09-2013.01 —— 研究助理教授,香港中文大学,化学系
2005.09-2007.07 —— 博士后,麻省理工学院,化学系 (with Prof. T. F. Jamison)
荣誉及奖励:
2017 —— Thieme化学期刊奖;有机化学研究员
2016 —— 深圳市南山区领航人才B类;南方科技大学优秀教学奖;南方科技大学青年教师教学竞赛奖
2015 —— 广东省本科高校化学类专业教学指导委员会委员
2013 —— 深圳市海外高层次人才B类;ACS Excellence in Science Symposium 最佳海报奖
2011 —— 亚洲核心计划讲学奖(新加坡)
2010 —— 亚洲核心计划讲学奖(日本)
2005-2007 —— 裘槎奖学金
新材料产业—先进石化工新材料—专用化学品及材料制造—专用化学品及材料制造
Diastereodivergent Hydrosilylative Enyne Cyclization Catalyzed by N-Heterocyclic Carbene-Ni(0) .Yu, M.; Yong, X.F.; Gao, W.W.; Ho, C.-Y. J. Chem. 2021, 39 , 1587.
NHC/Nickel(II)-Catalyzed [3+2] Cross-Dimerization of Unactivated Olefins and Methylenecyclopropanes. Huang, J.-Q.; Ho, C.-Y., Angewandte Chemie International Edition. 2020, 59 , 5288.
NHC-Ni catalyzed enantioselective synthesis of 1,4-dienes by cross-hydroalkenylation of cyclic 1,3-dienes and heterosubstituted terminal olefins. Chen, Y.; Dang, L.; Ho, C.-Y., Nature Communications. 2020, 11, 2269.
NHC-Ni catalyzed 1,3- and 1,4-diastereodivergent heterocycle synthesis from hetero-substituted enyne. Yong, X.; Gao, W.; Lin, X.; Ho, C.-Y., Communications 2020, 3, 50.
NHC-Ni(0) Catalyzed Diastereodivergent Hydroacylative Enyne Cyclization: Synthesis of Heterocycles bearing gamma-Enone. Advanced Synthesis & Catalysis. Yong, X.; Ng, E.; Zhen, Z.; Lin, X.; Gao, W.; Ho, C.-Y., 2020, 362 , 4164.
Applications of (NHC)Ni(II) Catalyzed [3+2] Hydroalkenylation-Rearrangement Cascades. Yong, X.; Huang, J.-Q., Ho, C.-Y., Chinese Journal of Organic Chemistry. 2020, 40 , 3327. (invited special issue: Prof. Henry N. C. Wong)
[(NHC)(NiH)-H-II]-Catalyzed Cross-Hydroalkenylation of Cyclopropenes with Alkynes: Cyclopentadiene Synthesis by [(NHC)Ni-II]-Assisted C-C Rearrangement. Huang, J.-Q.; Ho, C.-Y, Chem. Int. Ed. 2019, 58, 5702.
Electronic Effects on Chiral NHC–Transition-Metal. Yong, X., Thurston, R. & Ho, C.-Y,Synthesis 2019, 51, 2058.
Synthesis and Study of Au(III)-Indolizine Derivatives: Turn-on Luminescence by Photo-induced Control Release. Yang, J.; Zhu, Y.; Tse, A. K.-W.; Zhou, X.; Chen, Y.; Tse, Y. C.;* Wong, K. M.-C.;* Ho, C.-Y, Commun. 2019, 55, 4471.
(NHC)NiH-Catalyzed Regiodivergent Cross-Hydroalkenylation of Vinyl Ether with α-Olefin: 1,2- and 1,3-Disubstituted Allyl Ether Syntheses. Chen, W.; Li, Y.; Chen, Y.; Ho, C.-Y, Chem. Int. Ed. 2018, 57, 2677.
(NHC)NiH-Catalyzed Intermolecular Regio- and Diastereoselective Cross-Hydroalkenylation of Endocyclic Dienes with α-Olefins. Lian, X.; Chen, W.; Dang, L.; Li, Y.; Ho, C.-Y.* Chem. Int. Ed. 2017, 56, 9048.
Mechanism and Regioselectivities of (NHC)Nickel(II)hydride-Catalyzed Cycloisomerization of Dienes: A Computational Study. Gao, Y.; Houk, K. N.; Ho, C.-Y.*; Hong, X.* Biomol. Chem. 2017, 15, 7131.
Catalytic Asymmetric Hydroalkenylation of Vinylarenes: Electronic Effects of Substrates and Chiral N-Heterocyclic Carbene Ligands Ho, C.-Y.*; Chan, C.-W.; He, L. Chem. Int. Ed. 2015, 54, 4512.
Substituted 1,3-cyclohexadiene synthesis by NHC-Nickel(0) catalyzed [2+2+2] cycloaddition of 1,n-Enyne”. Zhao, J.-P.; Chan, S.-C.; Ho, C.-Y.* Tetrahedron 2015, 71, 4426.
Computational Exploration of Mechanism and Selectivities of NHC-Ni(II)hydride Catalyzed Hydroalkenylations of Styrene with a-Olefins. Hong, X.; Wang, J.; Yang, Y.-F.; He, L.; Ho, C.-Y.*; Houk, K. N.* ACS Catal. 2015, 5, 5545.
Nitrate-Enhanced NHC-NiH Catalyzed Tail-to-Tail Vinyl Ether Dimerization. He, L.; Ho, C.-Y.* 2014, 25, 2738.
Medium-Sized Heterocycle Synthesis by the Use of Synergistic Effects of Ni-NHC and γ‑Coordination in Cycloisomerization. Ho, C.-Y.*; He, L. J. Chem. 2014, 79, 11873.
Shuffle off the Classic -Si Elimination by Ni-NHC Cooperation: Implication for C-C Forming Reactions Involving Ni-Alkyl-β-Silanes. Ho, C.-Y.*; He, L. Commun. 2012, 48, 1481.
Catalytic Intermolecular Tail-to-Tail Hydroalkenylation of Styrenes with alpha Olefins: Regioselective Migratory Insertion Controlled by a Nickel/N-Heterocyclic Carbene. Ho, C.-Y.*; He, L. Chem. Int. Ed. 2010, 49, 9182.
Cyanative Alkene-Aldehyde Coupling: Ni(0)-NHC-Et2AlCN Mediated Chromanols Synthesis with High cis-Selectivity at room temperature. Ho, C.-Y.* Commun. 2010, 46, 466.
Nitrile assisted, Bronsted acid catalyzed regio and stereoselective diarylphosphonylation of allyl silyl ethers. Ho, C.-Y.*; Chan, C.-W.; Wo, S.-K.; Zuo, Z.; Chan, L.-Y. Biomol. Chem. 2010, 8, 3480.
Nitrile assisted, Bronsted acid catalyzed regio and stereoselective diarylphosphonylation of allyl silyl ethers. Ho, C.-Y.*; Chan, C.-W.; Wo, S.-K.; Zuo, Z.; Chan, L.-Y. Org. Chem. 2010, 8, 3480.
Alpha Olefins as Alkenylmetal Equivalents in Catalytic Conjugate Addition Reactions. Ho, C.-Y.; Ohmiya, H.; Jamison, T. F.* Chem. Int. Ed. 2008, 47, 1893.
Highly Chemoselective Reductive Amination of Carbonyl Compounds Promoted by InCl3/Et3SiH/MeOH System. Lee, O.-Y.; Law, K.-L.; Ho, C.-Y.; Yang, D.* Org. Chem. 2008, 73, 8829.
Highly Selective Coupling of Alkenes and Aldehydes Catalyzed by NHC–Ni–P(OPh)3: Synergy Between a Strong σ-Donor and a Strong π-Acceptor. Ho, C.-Y.; Jamison, T. F.* Chem. Int. Ed. 2007, 46, 782.
Nickel-Catalyzed Coupling of Alkenes, Aldehydes, and Silyl Triflates. Ng, S.-S.; Ho, C.-Y.; Jamison, T. F.* Am. Chem. Soc. 2006, 128, 11513.
Nickel-Catalyzed, Carbonyl-Ene-Type Reactions: Selective for Alpha Olefins and More Efficient with Electron-Rich Aldehydes. Ho, C.-Y.; Ng, S.-S.; Jamison, T. F.* Am. Chem. Soc. 2006, 128, 5326.
Fluorinated Chiral Secondary Amines as Catalysts for Epoxidation of Olefins with Oxone. Ho, C.-Y.; Chen, Y.-C.; Wong, M.-K.; Yang, D.* Org. Chem. 2005, 70, 898.